The Main Contributor to Chronic Inflammation

Mascari, Brooke - January 31st, 2025 (Updated February 15th, 2025)

In today’s modern diet, seed oils have become nearly impossible to avoid. Found in everything from salad dressings to fried foods and even so-called “health” snacks, these oils have infiltrated our food supply under the guise of being heart-healthy. However, research has shown that many of these oils contribute to systemic inflammation, cellular damage, insulin resistance, and long-term health issues. Chronic inflammation is at the root of numerous diseases, including cardiovascular disease, obesity, diabetes, and autoimmune disorders. Many doctors suggest that inflammation is THE cause of ALL diseases and auto-immune diseases!

So despite their widespread use, seed oils do more harm than good.

Understanding the impact of these oils on your body is crucial for making informed dietary choices. In this article, we will uncover the most inflammatory seed oils, why they pose a risk to your health, and which healthier alternatives you can use to support your well-being. By making simple swaps, you can significantly reduce inflammation and improve your hormone balance and overall health, all while enjoying delicious and nourishing foods.

The Most Inflammatory Seed Oils

Seed oils, often marketed as "heart-healthy," are found in numerous processed foods, nearly all restaurant meals, and even home kitchens. However, many of these oils are highly processed and contain unhealthy fats that trigger inflammation.

1. Soybean Oil

A staple in many processed foods, soybean oil is deceptively unhealthy. It’s loaded with omega-6 fatty acids that disrupt the body's delicate balance, promoting inflammation that contributes to obesity, heart disease, and autoimmune conditions. This oil sneaks into salad dressings, fried foods, and snacks, making it a silent but serious health threat.

Soy also contains phytoestrogens, specifically isoflavones, which are plant compounds that mimic estrogen in the body by binding to estrogen receptors. While they have a much weaker effect than the body's natural estrogen, they can still influence hormone balance, potentially supporting or disrupting estrogen-related processes depending on individual health factors.

2. Corn Oil

Corn oil, frequently used in deep-fried foods and margarine is another omega-6 powerhouse. Extracted using harsh chemical solvents like hexane, this oil is prone to oxidation, forming damaging free radicals that wreak havoc on your cells. Despite its widespread use, it’s far from a "healthy" choice.

3. Canola Oil (Rapeseed Oil)

Often praised for its low saturated fat content, canola oil undergoes intense processing, including high heat and chemical refining, leading to the oxidation of its polyunsaturated fats. This results in inflammatory compounds that may contribute to chronic illnesses. Additionally, much of the canola oil on the market is derived from genetically modified crops, raising concerns about pesticide contamination.

4. Sunflower Oil

Despite its mild taste and frequent use in cooking, traditional sunflower oil is another omega-6-rich culprit. It can tip the body's inflammation scale when consumed in excess, particularly in diets lacking sufficient omega-3 fatty acids. This imbalance can contribute to joint pain, metabolic disorders, and cardiovascular issues.

5. Safflower Oil

Touted as a neutral cooking oil, safflower oil is anything but neutral when it comes to inflammation. It is extremely high in linoleic acid, an omega-6 fatty acid that promotes systemic inflammation when over-consumed. Without a counterbalance of anti-inflammatory fats, safflower oil becomes a silent contributor to chronic health problems.

6. Cottonseed Oil

One of the most processed and chemically treated oils available, cottonseed oil often contains pesticide residues and is commonly hydrogenated, creating dangerous trans fats. These fats have been directly linked to increased risks of heart disease, insulin resistance, and systemic inflammation. Avoiding cottonseed oil is a key step in protecting your health.

7. Grapeseed Oil

Grapeseed oil is high in omega-6 fatty acids, particularly linoleic acid, which promotes inflammation and disrupts the omega-6 to omega-3 balance, contributing to chronic diseases. It is typically extracted using chemical solvents like hexane and subjected to high heat, a process that degrades the oil and introduces toxic byproducts.

Being highly polyunsaturated, grapeseed oil oxidizes easily, leading to the formation of free radicals that damage cells, accelerate aging, and contribute to metabolic dysfunction. Additionally, its processing and refinement can result in harmful trans fats, which are linked to heart disease and insulin resistance.

8. Rice Bran Oil

Rice bran oil contains a high percentage of inflammatory omega-6 fatty acids, which can increase systemic inflammation and raise the risk of chronic disease. It is typically refined using chemical solvents like hexane, which often leave behind toxic residues that burden the liver. The refining process also depletes antioxidants and contributes to oxidative stress, leading to cellular dysfunction. Additionally, since rice is prone to absorbing arsenic from the soil, traces of this toxic element are often present in rice bran oil, posing potential long-term health risks.

9. Refined Palm Oil

Refined palm oil undergoes an extensive processing and deodorizing process that removes beneficial nutrients while introducing harmful chemical byproducts. The heating and refining process also produces oxidized lipids, which contribute to oxidative stress and inflammation. Additionally, some refined palm oils contain trans fats, which negatively impact heart health and disrupt hormone balance. Beyond its health risks, large-scale palm oil production contributes to deforestation and the destruction of natural ecosystems, indirectly affecting human health through pollution and environmental disruption.

A breakdown by Dr. Cate Shanahan:

Always Avoid the Evil 8: Canola (also called “Rapeseed”), Corn, Cottonseed, Soy, Sunflower, Safflower, Grapeseed, and Rice bran.

ALSO TOXIC: Refined Palm oil. (It’s not very high in PUFAs, but the refining is often more intense.)

PLUS: Anything that says hydrogenated because it’s going to start with refined oil and further process to create trans fats.

Vegetable oil is an industry term that sometimes includes olive oil, peanut, and coconut. However, when you see the word vegetable oil on the ingredients, it’s not going to be first press, unrefined olive, peanut, or coconut. It will be one of the cheap, refined PUFA-rich, seed oils listed above.”

Why Are These Oils Inflammatory?

The primary reasons seed oils contribute to inflammation:

High Omega-6 Fatty Acid Content: While omega-6 fats are essential in small amounts, our modern diets contain an excessive ratio of omega-6 to omega-3, which disrupts cellular balance and triggers chronic inflammation.

Oxidation and Rancidity: Many seed oils are exposed to heat, light, and air during processing and storage, causing oxidation. Consuming oxidized oils increases oxidative stress in the body, damaging cells and contributing to aging and disease.

Chemical Processing: The refining process involves high heat, chemical solvents, and bleaching agents that strip oils of beneficial nutrients while introducing toxic byproducts that we end up consuming in these oils.

Trans Fat Formation: Some seed oils undergo hydrogenation, turning them into trans fats, which are known to increase the risk of heart disease, diabetes, and systemic inflammation.

Insulin Resistance and Seed Oils

Seed oils, particularly those high in omega-6 fatty acids like linoleic acid, have been linked to insulin resistance, weight gain, and obesity in the United States. Research suggests that excessive intake of linoleic acid can lead to increased fat cell size and may interfere with satiety signals, promoting overeating and cravings.

Studies on animals have shown that diets high in soybean oil result in greater weight gain and insulin resistance compared to diets high in other fats. Additionally, the oxidation of polyunsaturated fats in seed oils contributes to chronic inflammation, which plays a key role in disrupting insulin signaling and metabolic function. As a result, the widespread consumption of seed oils in processed foods may be a major driver of obesity and metabolic disorders.

Omega-6 is Supposed to be Healthy; Why is it Harmful?

Again, omega-6 fatty acids are polyunsaturated fats that the body needs in small amounts for proper function. However, the modern diet contains an excessive amount of omega-6, creating an imbalance with omega-3 fatty acids. Here’s why this imbalance is harmful:

  1. Increased Chronic Inflammation: Omega-6 fats, particularly linoleic acid, are converted into arachidonic acid, which is a precursor to inflammatory compounds called prostaglandins and leukotrienes. When consumed in excess, these compounds fuel systemic inflammation, contributing to diseases such as arthritis, heart disease, and autoimmune disorders.

  2. Imbalanced Omega-6 to Omega-3 Ratio: Our ancestors consumed an omega-6 to omega-3 ratio of approximately 1:1. Today, due to processed foods and seed oils, this ratio has skyrocketed to 15:1 or even 20:1!! This imbalance impairs cellular function, promotes oxidative stress, and weakens the body’s ability to fight inflammation.

  3. Oxidative Stress and Free Radicals: Many omega-6-rich oils are unstable and prone to oxidation when exposed to heat and light. When consumed, these oxidized oils contribute to the formation of free radicals, which damage cells and accelerate aging, increasing the risk of cancer and neurodegenerative diseases.

  4. Negative Impact on Heart Health: While omega-6 has been promoted as heart-healthy, research suggests that excessive intake can increase the risk of cardiovascular disease by promoting blood clot formation, arterial plaque buildup, and endothelial dysfunction. This contradicts the long-standing belief that omega-6 is beneficial for the heart.

  5. Compromised Immune Function: Chronic inflammation triggered by excessive omega-6 intake can suppress immune function over time. This can lead to increased susceptibility to infections, autoimmune conditions, and even mental health disorders like depression and anxiety.

Healthier Alternatives to Seed Oils

Instead of using inflammatory seed oils, consider incorporating these healthier fats into your diet:

Extra Virgin Olive Oil (EVOO)

Rich in monounsaturated fats and antioxidants, extra virgin olive oil has been shown to reduce inflammation and support heart health. It contains powerful polyphenols that protect cells from oxidative damage and improve overall well-being!

Unrefined Coconut Oil

Coconut oil is primarily composed of medium-chain triglycerides (MCTs), which provide a quick energy source and have antimicrobial properties. Unlike seed oils, coconut oil is stable at high temperatures, making it ideal for cooking.

Avocado Oil

Avocado oil is high in heart-healthy monounsaturated fats and contains antioxidants that reduce inflammation. It has a high smoke point, making it a good option for sautéing and roasting.

Grass-Fed Butter & Ghee

Grass-fed butter and ghee are excellent sources of saturated fats and fat-soluble vitamins like A, D, and K2. They provide a stable cooking fat option without the inflammatory properties of seed oils.

Animal-Based Fats (Tallow & Lard)

These traditional cooking fats, when sourced from pasture-raised animals, contain beneficial fatty acids that support brain health and cellular function. They are also stable at high heat, making them great for frying and roasting!

Your health is in your hands, and the choices you make in your kitchen can define your future! Even though these toxins and bad seed oils are in so many of our food sources, and you likely have experienced some sickness and imbalance due to these things, our health is still our responsibility. The war against chronic inflammation starts with what’s on your plate. By eliminating inflammatory seed oils and replacing them with nourishing, anti-inflammatory fats, you can reclaim your vitality, support your body's natural healing processes, balance your hormones, and take control of your well-being.

Imagine waking up with more energy, experiencing less pain, and knowing that every meal you prepare is fueling your body the way nature intended. The journey to better health begins with a single step—ditch the seed oils, embrace real fats, and watch your body thrive. It’s time to say goodbye to inflammation and hello to a vibrant, healthier you!

Sources:

https://drcate.com/list-of-good-fats-and-oils-versus-bad/

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